Professor George Banting

Research summary

Identification and characterisation of:

1. intramolecular signals involved in the faithful sorting/targeting/retention of integral membrane proteins specific to different intracellular organelles
2. the intracellular machinery required to recognise these signals.

This research involves techniques from the fields of both molecular and cell biology. Interest is focused on the Golgi apparatus, specifically the trans-Golgi Network (TGN). The TGN is a major site of intracellular protein sorting at the exit site from the Golgi stack.

We have particular interest in a specific integral membrane protein, TGN38, which cycles between the TGN and the cell surface. The regulated expression of wild type and ...

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Recent publications

• Beesley, J, Baum, H, Hodgson, L, Verkade, P, Banting, G & Woolfson, D, 2018, ‘Modifying self-assembled peptide cages to control internalization into mammalian cells’. Nano Letters.
• Edgar, JR, Manna, P, Nishimura, S & Banting, G, 2016, ‘Tetherin is an exosomal tether’. eLife, vol 5.

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View complete publications list in the University of Bristol publications system