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Dr Steven Burston

Dr Steven Burston

Dr Steven Burston
B.Sc. (Hons.), PhD

Senior Lecturer

Office C101b
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

+44 (0) 117 331 2137

Summary

Teaching

Biophysics and Molecular Life Sciences I

Biophysics and Molecular Life Sciences II

Biological Chemistry

Macromolecular Structure, Dynamics and Function

The Dynamic Proteome

Synthetic Biology

Advanced Options in Biochemistry – Molecular basis of disease

MSc Core Skills

Expertise

Proteins are the workforce of every cell and are synthesised by assembling amino acids in a particular sequence which is dictated by the genetic code of DNA. However, it is the folding of this string of amino acids into a unique three-dimensional shape which gives proteins their ability to function. My research focuses on the molecular mechanisms of protein machines, termed molecular chaperones, which assist "protein quality control" within the biological cell i.e. they ensure that proteins are correctly folded in the right place at the right time, or alternatively that they are unfolded and degraded when necessary. This regulation of protein folding and degradation is essential for the survival of each cell. There are a number of diseases result in the malfunction of this system, which in turn may give rise to observed symptoms. Examples of these include BSE/CJD, Alzheimer's Disease, Huntington's Disease.

  • protein folding
  • molecular chaperones
  • molecular motors
  • Memberships

    Organisations

    School of Biochemistry

    Other sites

    Recent publications

    View complete publications list in the University of Bristol publications system

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