Browse/search for people

Dr Lucy Crompton

Dr Lucy Crompton

Dr Lucy Crompton
B.Sc.(Manc.), MRes. (Imperial College London), PhD

Senior Research Associate

Area of research

The use of iPSC models to investigate the role of astrocytes in neurodegenerative disease

Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Tel. +44 (0) 117 33 11829

Research summary

- The use of patient derived induced Pluripotent Stem Cells (iPSCs) to investigate Parkinsons disease and Alzheimer's disease.

- In particular my work looks at the role astrocytes play in these diseases.

- We generate specific subpopulations of neurons and astrocytes from the iPSCs and we use these to model the diseases.

- In particular I am interested in how astrocytes support neurons and how defective support may pre-empt disease.

Read more >

Biography

My research is focused on the application of stem cells for the study of neurodevelopment and neurodegeneration.  I have over 12 years of experience in the culture of multiple types of stem cell and their differentiation into neural cells, as well as the reprogramming of patient derived cells into stem cells. My current research focuses on Parkinson’s disease and I am investigating how neuroinflammation, in particular the role of astrocytes, contributes to Parkinson’s disease pathology. In brief I am using a hiPSC derived platform to study how astrocytes protect and support neurons but also how chronic disease generates neurotoxic ...

Read more >

Recent publications

Read more >

View complete publications list in the University of Bristol publications system

Edit this profile If you are Dr Lucy Crompton, you can edit this page. Login required.

All details on one page > for printing etc.