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Professor Harry Mellor

Professor Harry Mellor

Professor Harry Mellor
B.Sc.(Edin.), Ph.D.(Bristol)

Professor of Biochemistry

Area of research

Endothelial cell dynamics in angiogenesis

Office C49
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Tel. +44 (0) 117 331 2174

Research summary

The cytoskeleton forms a dynamic framework inside cells, supporting their shape and their movement.  My lab focusses on the cytoskeleton of endothelial cells, the cell that line blood vessels.  In healthy blood vessels, the endothelial cells control the passage of oxygen and nutrients from the blood to the tissue below, and return waste products in the opposite direction.  Their cytoskeleton regulates this barrier function, and also controls the shape of the cells to allow blood to flow smoothly over the surface.  Dysregulation of the cytoskeleton leads to disruption of the normal barrier and pathological flow.

When tissues become ...

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  • BSc (Hons) Biochemistry, University of Edinburgh (1988)
  • PhD Biochemistry, University of Bristol, School of Biochemistry, (1992)
  • Juvenile Diabetes Foundation International Personal Fellowship, Penn State University (1993-1995)
  • Postdoctoral Fellow, Cancer Research UK, London Research Institute (1995-1998)
  • Wellcome Trust Career Development Fellowship, University of Bristol (1998-2003)
  • Welcome Trust University Award, University of Bristol (2003-2008)
  • Reader in Biochemistry, University of Bristol (2005-2010)
  • Professor of Biochemistry, University of Bristol (2010-present)
  • Graduate Dean for Life Sciences (2018 - present)

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Selected publications

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View complete publications list in the University of Bristol publications system

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