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Dr Binyam Mogessie

Dr Binyam Mogessie

Dr Binyam Mogessie
PhD, BSc

Sir Henry Dale Research Fellow

Area of research

Mechanisms of chromosome segregation in mammalian eggs

Office C49c
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Tel. +44 (0) 117 331 1595

Research summary

Mogessie Lab Webpage  

Every human life starts when an egg is fertilised by a sperm. Fertilisation unites two sets of chromosomes, one from each parent, to form a genetically unique embryo. For poorly understood reasons, eggs frequently contain incorrect number of chromosomes. This prevents the formation of healthy embryos and very often leads to embryonic deaths in humans. In order to clinically prevent embryo deaths and spontaneous abortions as well as to treat infertility, it is vital to understand the basic processes that produce heathy eggs inside the body. Recently, we found that actin, one of the dynamic structures ...

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My scientific career started at Jacobs University Bremen (Germany) where I studied Biochemistry and Cell Biology as an undergraduate student. After receiving my BSc in 2007, I moved to the UK and joined the laboratory of Anne Straube as a PhD student first at the Marie Curie Research Institute (Surrey) and later at the Centre for Mechanochemical Cell Biology (Warwick). During my PhD, I primarily investigated the cellular mechanisms that reorganise the microtubule cytoskeleton during skeletal muscle differentiation. I found that a novel isoform of the microtubule-associated protein MAP4 is required for antiparallel organisation of microtubules in this system (Read ...

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Recent publications

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View complete publications list in the University of Bristol publications system

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