Dorothy Hodgkin Building,
Whitson Street,
Bristol
BS1 3NY
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Tel. +44 (0) 117 331 3048
kei.cho@bristol.ac.uk
Research in Cho group focuses on a wide range of projects from molecular mechanisms of synaptic plasticity in the brain to pathological aspects of the central nervous system (CNS) including Alzheimer's disease. This is achieved through electrophysiological recordings, calcium imaging, molecular biology, cell culture, gene transfection, immunocytochemical techniques and MRI-brain imaging.
The plastic nature of synapses means that long-term potentiation (LTP, a prolonged increase in synaptic transmission) and long-term depression (LTD, a long-lasting depression of synaptic transmission) can be induced.
Using brain slice electrophysiology and calcium imaging techniques, our findings from the hippocampus and perirhinal cortex have suggested a ...
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