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Miss Ashley Tyrer


During my PhD, I first conducted Dynamic Causal Modelling (DCM) of task-based EEG data to examine how the connectivity of behavioural memory circuits are compromised in patients with Alzheimer's disease, and how this may differ from healthy controls. In my current study, I am using task-based fMRI to investigate the role of Noradrenaline in optimal decision-making, also employing DCM computational techniques. I am also examining the effect of Noradrenaline on state-action prediction errors using an Active Inference model, to estimate subject-specific parameters of internal model flexibility and decay.