Professor Mick Bailey

Research summary

Summary

The mucosal immune system is exposed to pathogens but also to food and commensal bacteria, and must produce active immune responses or tolerance, respectively. The ability to discriminate accurately between the two is important, since making the wrong decision can result in allergy or in susceptibility to infectious diseases. There is increasing evidence that events during early life can influence individual susceptibility to allergy, by affecting the process of colonisation of the intestine with commensal microbiota, exposure to pathogenic organisms, or through the level of exposure to food antigens before weaning. Similar early-life events affecting microbial colonisation are also ...

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Biography

Teaches
BVSc Veterinary Science
BSc Cellular and Molecular Medicine

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Recent publications

• Bailey, M, Thomas, A, Francis, O, Stokes, C & Smidt, H, 2019, ‘The dark side of technological advances in analysis of microbial ecosystems’. Journal of Animal Science and Biotechnology.
• Christoforidou, Z, Burt, R, Mulder, I, Gill, BP, Pluske, J, Kelly, D, Stokes, CR, Bailey, M & Lewis, MC, 2018, ‘Development of immune cells in the intestinal mucosa can be affected by intensive and extensive farm environments, and antibiotic use’. Frontiers in Immunology, vol 9.

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View complete publications list in the University of Bristol publications system