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Publication - Dr Lindsay Nicholson

    The Immune System


    Nicholson, L, 2016, ‘The Immune System’. Essays in Biochemistry, vol 60., pp. 275-301


    All organisms are connected in a complex web of relationships. Although many of these are benign, not all are, and everything alive devotes significant resources to identifying and neutralizing threats from other species. From bacteria through to primates, the presence of some kind of effective immune system has gone hand in hand with evolutionary success. This article focuses on mammalian immunity, the challenges that it faces, the mechanisms by which these are addressed, and the consequences that arise when it malfunctions.

    “Great fleas have little fleas upon their backs to bite 'em, And little fleas have lesser fleas, and so ad infinitum.” Augustus De Morgan (1872)

    Full details in the University publications repository