Dr Allison Blair

Dr Allison Blair
B.Sc., Ph.D.(St.And.)

Principal Clinical Scientist

Office B25c
Biomedical Sciences Building,
University Walk, Clifton BS8 1TD
(See a map)

Cancer Stem Cells and Haematopoietic Stem Cell Therapy, including studying the characteristics of leukaemia cells to increase our understanding of the differences between stem cells that can initiate leukaemia and haemopoietic stem cells that produce normal blood cells; developing new therapeutic strategies targeted at leukaemia stem cells; ex vivo expansion of normal blood stem cells to produce therapeutic quantities of red blood cells, platelets and neutrophils for use in transfusion and transplantation.

Our research is focused on the biology of childhood leukaemia and on ex vivo expansion of haemopoietic stem cells for therapeutic use ...

Morgan, R, Ridsdale, J, Payne, M, Heesom, K, Wilson, MC, Davidson, A, Greenhough, A, Davies, S, Williams, A, Blair, A, Waterman, ML, Tonks, A & Darley, R, 2019, ‘LEF-1 drives aberrant β-catenin nuclear localization in myeloid leukemia cells’. Haematologica, vol 104., pp. 1365-1377
Menendez-Gonzalez, JB, Sinnadurai, S, Gibbs, A, Thomas, Konstantinou, M, Garcia-Valverde, A, Boyer, M, Wang, Z, Boyd, AS, Blair, A, Morgan, RG & Rodrigues, NP, 2019, ‘Inhibition of GATA2 restrains cell proliferation and enhances apoptosis and chemotherapy mediated apoptosis in human GATA2 overexpressing AML cells’. Scientific Reports, vol 9.