Professor Stephen Mann

Summary

The general theme of Professor Mann’s research is concerned with the chemical synthesis, characterization and emergence of complex forms of organized matter. His current research activities include: biomimetic materials chemistry, synthesis and self-assembly of nanoscale objects and functional bionanomaterials, complexity and emergent behaviour in hybrid nanostructures, solvent-free liquid proteins, and protocell design and construction. 

Keywords

• Synthetic Cellularity
• Protocells
• Origin of Life
• Nanotectonics
• Bionanochemistry
• Inorganic Morphosynthesis
• Biomineralization

Expertise

Research Themes: - Biomineralization - Biomimetic Materials Chemistry - Magnetic Proteins and Bioinorganic Nanocomposites - Template-directed Synthesis - Self-assembled Inorganic Materials - Inorganic Morphosynthesis - Nanotectonics - Bionanochemistry - Meso-structured Inorganic-organic Materials - Life as a Nanoscale Phenomenon - Protein Melts - Self-assembly and Transformation of Nano-objects

Memberships

Organisations

School of Chemistry

Other sites

• Chemistry

Links

•   Personal web page
•   Centre for Protolife Research
•   Centre for Organized Matter Chemistry

Selected publications

• Tang, T-Y, Hak, CRC, Thompson, AJ, Kuimova, MK, Williams, DS, Perriman, AW & Mann, S, 2014, ‘Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model’. Nature Chemistry, vol 6., pp. 527-533
• Brogan, APS, Sharma, KP, Perriman, AW & Mann, S, 2014, ‘Enzyme activity in liquid lipase melts as a step towards solvent-free biology at 150 °C’. Nature Communications, vol 5.
• Li, M, Huang, X, Tang, T-Y & Mann, S, 2014, ‘Synthetic cellularity based on non-lipid micro-compartments and protocell models’. Current Opinion in Chemical Biology, vol 22., pp. 1-11
• Koga, S, Williams, D, Perriman, A & Mann, S, 2011, ‘Peptide-nucleotide microdoplets as a step towards a membrance-free protocell model’. Nature Chemistry, vol 3., pp. 720 - 724
• Huang, X, Li, M, Green, DC, Williams, DS, Patil, AJ & Mann, S, 2013, ‘Interfacial Assembly of Protein-polymer Nano-conjugates into Stimulus-Responsive Biomimetic Protocells’. Nature Communications, vol 4.
• Li, M, Harbron, R, Weaver, J, Binks, B & Mann, S, 2013, ‘Electrostatically gated membrane permeability in inorganic protocells’. Nature Chemistry, vol 5., pp. 529-536
• Qiao, Y, Li, M, Booth, R & Mann, S, 2017, ‘Predatory behaviour in synthetic protocell communities’. Nature Chemistry, vol 9., pp. 110-119

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Recent publications

• Wang, L, Lin, Y, Zhou, Y, Xie, H, Song, J, Li, M, Huang, Y, Huang, X & Mann, S, 2019, ‘Autonomic Behaviors in Lipase-Active Oil Droplets’. Angewandte Chemie - International Edition, vol 58., pp. 1067-1071
• Joesaar, A, Yang, S, Bögels, B, Linden, Avd, Pieters, P, Kumar, BV, Dalchau, N, Phillips, A, Mann, S & Greef, TFd, 2019, ‘DNA-based communication in populations of synthetic protocells’. Nature Nanotechnology, vol 14., pp. 369-378
• Wu, H, Zhang, Z, Mann, S & Briscoe, WH, 2019, ‘Hierarchical microfibrillar gels from evaporation-induced anisotropic self-assembly of in situ-generated nanocrystals’. Journal of Colloid and Interface Science, vol 558., pp. 78-84

View complete publications list in the University of Bristol publications system