Professor Mark Dillingham

Latest publications

• Hawkins, M, Dimude, JU, Howard, JAL, Smith, A, Dillingham, M, Savery, N, Rudolph, CJ & McGlynn, P, 2019, ‘Direct removal of RNA polymerase barriers to replication by accessory replicative helicases’. Nucleic Acids Research, vol 47., pp. 5100-5113
• Wilkinson, O, Martín-González, A, Kang, H, Northall, S, Wigley, DB, Moreno-Herrero, F & Dillingham, M, 2019, ‘CtIP forms a tetrameric dumbbell-shaped particle which bridges complex DNA end structures for double-strand break repair’. eLife, vol 8.
• Madariaga-Marcos, J, Pastrana, CL, Fisher, GL, Dillingham, MS & Moreno-Herrero, F, 2019, ‘ParB dynamics and the critical role of the CTD in DNA condensation unveiled by combined force-fluorescence measurements’. eLife, vol 8.
• Madariaga-Marcos, J, Hormeño, S, Pastrana, CL, Fisher, GL, Dillingham, MS & Moreno-Herrero, F, 2018, ‘Force determination in lateral magnetic tweezers combined with TIRF microscopy’. Nanoscale, vol 10., pp. 4579-4590
• Brüning, JG, Howard, JA, Myka, KK, Dillingham, MS & McGlynn, P, 2018, ‘The 2B subdomain of Rep helicase links translocation along DNA with protein displacement’. Nucleic Acids Research, vol 46., pp. 8917-8925
• Winter, AJ, Williams, C, Isupov, MN, Crocker, H, Gromova, M, Marsh, P, Wilkinson, OJ, Dillingham, MS, Harmer, NJ, Titball, RW & Crump, MP, 2018, ‘The molecular basis of protein toxin HicA– dependent binding of the protein antitoxin HicB to DNA’. Journal of Biological Chemistry, vol 293., pp. 19429-19440
• Fisher, GLM, Pastrana, CL, Higman, VA, Koh, A, Taylor, JA, Butterer, A, Craggs, TD, Sobott, F, Murray, H, Crump, MP, Moreno-Herrero, F & Dillingham, M, 2017, ‘The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere’. eLife, vol 6.
• Sanders, K, Lin, CL, Smith, AJ, Cronin, N, Fisher, G, Eftychidis, V, McGlynn, P, Savery, NJ, Wigley, DB & Dillingham, MS, 2017, ‘The structure and function of an RNA polymerase interaction domain in the PcrA/UvrD helicase’. Nucleic Acids Research, vol 45., pp. 3875-3887
• Myka, KK, Hawkins, M, Syeda, AH, Gupta, MK, Meharg, C, Dillingham, MS, Savery, NJ, Lloyd, RG & McGlynn, P, 2017, ‘Inhibiting translation elongation can aid genome duplication in Escherichia coli’. Nucleic Acids Research, vol 45., pp. 2571-2584
• Wilkinson, M, Troman, L, Kamil, WNIWA, Chaban, Y, Avison, MB, Dillingham, MS & Wigley, DB, 2016, ‘Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones’. eLife, vol 5.