Professor Ash Toye

Latest publications

• Severn, CE, Eissa, AM, Langford, CR, Parker, A, Walker, M, Dobbe, JG, Streekstra, GJ, Cameron, NR & Toye, AM, 2019, ‘Ex vivo culture of adult CD34+ stem cells using functional highly porous polymer scaffolds to establish biomimicry of the bone marrow niche’. Biomaterials, vol 225.
• Pellegrin, S, Haydn-Smith, K, Hampton-O'Neil, L, Hawley, B, Heesom, K, Fermo, E, Bianchi, P & Toye, A, 2019, ‘Transduction with BBF2H7/CREB3L2 upregulates SEC23A protein in erythroblasts and partially corrects the hypo-glycosylation phenotype associated with CDAII’. British Journal of Haematology, vol 184., pp. 876-881
• Satchwell, TJ, Wright, KE, Haydn-Smith, KL, Terán, FS, Moura, PL, Hawksworth, J, Frayne, J, Toye, AM & Baum, J, 2019, ‘Genetic manipulation of cell line derived reticulocytes enables dissection of host malaria invasion requirements’. Nature Communications, vol 10.
• Trakarnsanga, T, Ferguson, D, Daniels, D, Griffiths, R, Wilson, M, Mordue, K, Andrienko, T, Condie, A, McCahill, A, Mountford, JC, Toye, A, Anstee, D & Frayne, J, 2019, ‘Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation’. Stem Cell Research and Therapy, vol 10.
• Hampton-O'Neil, L, Severn, C, Gurung, S, Cross, S, Nobes, C & Toye, A, 2019, ‘Ephrin/Eph receptor interaction facilitates macrophage recognition of differentiating human erythroblasts’. Haematologica, vol 104.
• Moura, PL, Hawley, BR, Dobbe, JGG, Streekstra, GJ, Rab, M, Bianchi, P, van Wijk, R, Toye, AM & Satchwell, T, 2019, ‘PIEZO1 gain-of-function mutations delay reticulocyte maturation in hereditary xerocytosis’. Haematologica.
• Moura, PL, Iragorri, MAL, Francais, O, Le Pioufle, B, Dobbe, JGG, Streekstra, GJ, El Nemer, W, Toye, AM & Satchwell, T, 2019, ‘Reticulocyte and red blood cell deformation triggers specific phosphorylation events’. Blood Advances, vol 3., pp. 2653-2663
• Gurevich, D, Severn, C, Twomey, C, Greenhough, A, Cash, J, Toye, A, Mellor, H & Martin, P, 2018, ‘Live imaging of wound angiogenesis reveals macrophage orchestrated vessel sprouting and regression’. EMBO Journal, vol 37.
• Abbas, YM, Toye, AM, Rubinstein, JL & Reithmeier, RA, 2018, ‘Band 3 function and dysfunction in a structural context’. Current Opinion in Hematology, vol 25., pp. 163-170
• Huisjes, R, Satchwell, TJ, Verhagen, LP, Schiffelers, RM, van Solinge, WW, Toye, AM & van Wijk, R, 2018, ‘Quantitative measurement of red cell surface protein expression reveals new biomarkers for hereditary spherocytosis’. International Journal of Laboratory Hematology.