Professor Adam Perriman

Summary

Hybrid Biomolecular Systems

Adam Perriman is distinguished for pioneering research concerned with the construction and study of novel hybrid biomolecular systems using advanced physical techniques. His research interests are acutely interdisciplinary, are built on the solid foundations of fundamental science, and span the fields of nanotechnology, biophysical chemistry, and tissue engineering. His significant advances in these research areas has resulted in a number of invited seminars and colloquia, and Dr. Perriman has published thirteen papers in very high-impact scientific journals (out of a total of 28), including two articles in Nature Chemistry (including an invited cover)and a review in ACS Nano. His recent research into the unprecedented development of protein-polymer surfactant nanohybrids has generated extensive media coverage and featured in the popular science magazines New Scientist, Pop Sci and RSCs Chemistry World. In 2010 he was interviewed live on BB4’s Material World, which was broadcast live nationally. 

Research interests:

• Biophysics
• Protein bioconjugation
• Regenerative Medicine
• Functional Bionanomaterials
• Adult Stem Cell Membrane Re-enginering and Homing
• Small Angle Scattering (SANS and SAXS)

Biography

Adam Perriman is a member of the Biomedical Sciences Faculty at the University of Bristol in the School of Cellular and Molecular Medicine. He is also an Engineering and Physical Research Council (EPSRC) Early Career Fellow. He received his B.Sc from James Cook University before moving to the Research School of Chemistry at the Australian National University to complete Honours and PhD in 2007. After two years of postdoctoral work with Prof. S. Mann in the Centre for Organized Matter Chemistry (University of Bristol), he was awarded the Engineering and Physical Research Council (EPSRC) Cross-disciplinary Interfaces Fellowship.

Biography

Adam Perriman is a member of the Medical and Veterinary Sciences Faculty at the University of Bristol in the School of Cellular and Molecular Medicine. He is also an Engineering and Physical Research Council (EPSRC) Early Career Fellow. He received his B.Sc from James Cook University before moving to the Research School of Chemistry at the Australian National University to complete Honours and PhD in 2007. After two years of postdoctoral work with Prof. S. Mann in the Centre for Organized Matter Chemistry (University of Bristol), he was awarded the Engineering and Physical Research Council (EPSRC) Cross-disciplinary Interfaces Fellowship.

Keywords

• Biophysics Regenerative Medicine Functional Bionanomaterials Adult Stem Cell Membrane Re-enginering and Homing Small Angle Scattering (SANS and SAXS)

Memberships

Organisations

School of Cellular and Molecular Medicine

Other sites

• Chemistry

Recent publications

• Tuffin, J, Burke, M, Richardson, T, Johnson, T, Saleem, MA, Satchell, S, Welsh, GI & Perriman, A, 2019, ‘A Composite Hydrogel Scaffold Permits Self‐Organization and Matrix Deposition by Cocultured Human Glomerular Cells’. Advanced Healthcare Materials, vol 8.
• Deller, RC, Richardson, T, Richardson, R, Bevan, L, Zampetakis, I, Scarpa, F & Perriman, AW, 2019, ‘Artificial cell membrane binding thrombin constructs drive in situ fibrin hydrogel formation’. Nature Communications, vol 10.
• Xiao, W, Green, TIP, Liang, X, Delint, RC, Perry, G, Roberts, MS, Le Vay, K, Back, C, Ascione, R, Wang, H, Race, P & Perriman, A, 2019, ‘Designer artificial membrane binding proteins direct stem cells to the myocardium’. Chemical Science, vol 2019., pp. 7610 - 7618
• Zhou, Y, Jones, N, Pedersen, JN, Perez, B, Hoffmann, S, Petersen, S, Pedersen, J, Perriman, A, Kristensen, P, Gao, R & Guo, Z, 2019, ‘Insight into the structure and activity of surface-engineered lipase biofluids’. ChemBioChem, vol 20., pp. 1266-1272
• Armstrong, JP, Puetzer, JL, Serio, A, Guex, AG, Kapnisi, M, Breant, A, Zong, Y, Assal, V, Skaalure, SC, King, O, Murty, T, Meinert, C, Franklin, AC, Bassindale, PG, Nichols, MK, Terracciano, CM, Hutmacher, DW, Drinkwater, BW, Klein, TJ, Perriman, AW & Stevens, MM, 2018, ‘Engineering Anisotropic Muscle Tissue using Acoustic Cell Patterning’. Advanced Materials, vol 30.
• Pérez, B, Coletta, A, Pedersen, JN, Petersen, SV, Periole, X, Pedersen, JS, Sessions, RB, Guo, Z, Perriman, A & Schiøtt, B, 2018, ‘Insight into the molecular mechanism behind PEG-mediated stabilization of biofluid lipases’. Scientific Reports, vol 8.
• Tang, TY, Cecchi, D, Fracasso, G, Accardi, D, Coutable-Pennarun, A, Mansy, SS, Perriman, AW, Anderson, JL & Mann, S, 2018, ‘Gene-Mediated Chemical Communication in Synthetic Protocell Communities’. ACS Synthetic Biology, vol 7., pp. 339-346
• Ridolfo, R, Ede, BC, Diamanti, P, White, PB, Perriman, AW, van Hest, JC, Blair, A & Williams, DS, 2018, ‘Biodegradable, Drug-Loaded Nanovectors via Direct Hydration as a New Platform for Cancer Therapeutics’. Small, vol 14.
• Perry, G, Xiao, W, Welsh, G, Perriman, A & Lennon, R, 2018, ‘Engineered basement membranes: from in vivo considerations to cell-based assays’. Integrative biology.
• Deller, R, Carter, B, Zampetakis, I, Scarpa, F & Perriman, A, 2018, ‘The effect of surface charge on the thermal stability and ice recrystallization inhibition activity of antifreeze protein III (AFP III)’. Biochemical and Biophysical Research Communications, vol 495., pp. 1055-1060

View complete publications list in the University of Bristol publications system